Drupacine

Drupacine is a natural product, that can be isolated from Cephalotaxus harringtonia. Drupacine shows nematotoxicity and anticancer activity[1][2].

Product Specifications

CAS Number

[49686-57-9]

UNSPSC

12352005

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/drupacine.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@]2([H])[C@]34C[C@]1(O[C@](CN3CCC4)([H])C5=CC(OCO6)=C6C=C25)OC

Molecular Formula

C18H21NO5

Molecular Weight

331.36

References & Citations

[1]Li Y, et al. Preparation of Stereo-Divergent Compounds from the Natural Product Drupacine Based on Complexity-to-Diversity Strategy. Chem Biodivers. 2023 Jun;20 (6) :e202300263.|[2]Wen Y, et al. Nematotoxicity of drupacine and a Cephalotaxus alkaloid preparation against the plant-parasitic nematodes Meloidogyne incognita and Bursaphelenchus xylophilus. Pest Manag Sci. 2013 Sep;69 (9) :1026-33.