NL3

NL3 is a bacterial cystathionine γ-lyase inhibitor, with IC50s of 0.7 μM (bCSE) and 3.4 μM (hCSE) respectively. NL3 can be used for antimicrobial and circumventing bacterial resistance research[1].

Product Specifications

CAS Number

[2395867-03-3]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/nl3.html

Smiles

O=C(C1=NNC(CN2C=CC3=C2C=C(C4=CC5=C(C(Cl)=CC=C5)S4)C=C3)=C1)O

Molecular Formula

C21H14ClN3O2S

Molecular Weight

407.87

References & Citations

[1]Shatalin K, et al. Inhibitors of bacterial H2S biogenesis targeting antibiotic resistance and tolerance. Science. 2021 Jun 11;372 (6547) :1169-1175.