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Diprotin A

Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV) [1].

Product Specifications

CAS Number

[90614-48-5]

Product Name Alternative

Ile-Pro-Ile

UNSPSC

12352209

Hazard Statement

H302, H315, H319

Target

Dipeptidyl Peptidase

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/diprotin-a.html

Purity

99.58

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL

Smiles

CC[C@H](C)[C@@H](C(O)=O)NC([C@H]1N(C([C@H]([C@@H](C)CC)N)=O)CCC1)=O

Molecular Formula

C17H31N3O4

Molecular Weight

341.45

Precautions

H302, H315, H319

References & Citations

[1] Lee CS, et al. Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation. Sci Rep. 2016 Jul 6;6:29393.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

DPP-4

Citation 01

Nature. 2025 Jul;643 (8070) :192-200.|Cell Rep. 2025 Jan 25;44 (2) :115241.|Pharm Res. 2025 Jun;42 (6) :935-945.

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