ALKBH1-IN-2
ALKBH1-IN-2 (Compound 16) is a derivative of ALKBH1-IN-1 (HY-163385) . ALKBH1-IN-2 is an ALKBH1 inhibitor. ALKBH1-IN-2 can modulate the 6mA levels[1].
Product Specifications
UNSPSC
12352005
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alkbh1-in-2.html
Purity
99.16
Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NO)C1=CN(N=C1)C2=NC=C(C=N2)OCC3=CC=CC(OC(F)(F)F)=C3
Molecular Formula
C16H12F3N5O4
Molecular Weight
395.29
References & Citations
[1]Xiong L, et al. Discovery of a Potent and Cell-Active Inhibitor of DNA 6mA Demethylase ALKBH1. J Am Chem Soc. 2024 Mar 13;146 (10) :6992-7006.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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