Anti-Mouse CD3ε Antibody (KT3)

Anti-Mouse CD3ε Antibody (KT3) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse CD3ε. Anti-Mouse CD3ε Antibody (KT3) increases thymocytes proliferation. Anti-Mouse CD3ε Antibody (KT3) can be used for the research of immunology[1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

CD3

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-cd3ε-antibody-kt3.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseCD3εAntibody(KT3)]

Molecular Weight

(150 kDa)

References & Citations

[1]Hueber AO, et al. Thymocytes in Thy-1-/- mice show augmented TCR signaling and impaired differentiation. Curr Biol. 1997 Sep 1;7 (9) :705-8.|[2]Fischer KD, et al. Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor. Curr Biol. 1998 May 7;8 (10) :554-62.|[3]Mukasa A, et al. Extensive and preferential Fas/Fas ligand-dependent death of gammadelta T cells following infection with Listeria monocytogenes. Scand J Immunol. 2002 Sep;56 (3) :233-47.