Decursinol angelate

Decursinol angelate, a cytotoxic and protein kinase C (PKC) activating agent from the root of Angelica gigas, possesses anti-tumor and anti-inflammatory activities[1][2].

Product Specifications

CAS Number

[130848-06-5]

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

PKC

Type

Natural Products

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/decursinol-angelate.html

Purity

99.94

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C/C=C(C)\C(O[C@H]1CC(C=C(C=CC(O2)=O)C2=C3)=C3OC1(C)C)=O

Molecular Formula

C19H20O5

Molecular Weight

328.36

Precautions

H315, H319, H335

References & Citations

[1]Ahn KS, et al. Decursinol angelate: a cytotoxic and protein kinase C activating agent from the root of Angelica gigas. Planta Med. 1997 Aug;63 (4) :360-1.|[2]Lee S, et al. Anti-tumor activities of decursinol angelate and decursin from Angelica gigas. Arch Pharm Res. 2003 Sep;26 (9) :727-30.