GTSE1-IN-1
GTSE1-IN-1 is an orally active GTSE1 inhibitor. GTSE1-IN-1 can suppress GTSE1 transcription and expression. GTSE1-IN-1 can inhibit cancer cell proliferation by inducing cell cycle arrest and cell senescence through the persistence of DNA damage. GTSE1-IN-1 can be used for the research of cancer, such as colon and lung cancer[1].
Product Specifications
CAS Number
[3002034-34-3]
UNSPSC
12352211
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gtse1-in-1.html
Purity
98.07
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC1=CN=C(NC2=CC=C(N3CCN(C)CC3)C=C2)N=C1NC4=CC=C(N)C=C4
Molecular Formula
C21H24FN7
Molecular Weight
393.46
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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