Buparvaquone
Buparvaquone is a hydroxynaphthoquinone antiprotozoal agent related to parvaquone and atovaquone.
Product Specifications
CAS Number
88426-33-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Buparvaquone.html
Purity
99.64
Solubility
DMF : 25 mg/mL (ultrasonic) |DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 2 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C1C(CC2CCC(C(C)(C)C)CC2)=C(O)C(C3=C1C=CC=C3)=O
Molecular Formula
C21H26O3
Molecular Weight
326.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Müller J, et al. Buparvaquone is active against Neospora caninum in vitro and in experimentally infected mice. Int J Parasitol Drugs Drug Resist. 2015 Feb 13;5 (1) :16-25.|[2]Reimão JQ, et al. Effectiveness of liposomal buparvaquone in an experimental hamster model of Leishmania (L.) infantum chagasi. Exp Parasitol. 2012 Mar;130 (3) :195-9.|[3]Garnier T, et al. In vivo studies on the antileishmanial activity of buparvaquone and its prodrugs. J Antimicrob Chemother. 2007 Oct;60 (4) :802-10.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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