Klotho beta, Human (HEK293, His)
Klotho beta protein plays a critical role in the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), a key enzyme controlling bile acid synthesis. Although its glycosidase activity may be inactive, Klotho beta enhances the binding ability of FGFR1 and FGFR4 to FGF21, promoting their interaction. Klotho beta Protein, Human (HEK293, His) is the recombinant human-derived Klotho beta protein, expressed by HEK293 , with C-His labeled tag.
Product Specifications
Product Name Alternative
Klotho beta Protein, Human (HEK293, His), Human, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/klotho-beta-protein-human-hek293-his.html
Purity
97.0
Molecular Formula
152831 (Gene_ID) Q86Z14 (M30-T983) (Accession)
Molecular Weight
Approximately 112-140 kDa due to the glycosylation.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
Frequently Asked Questions
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