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Regorafenib-d3

Regorafenib-d3 (BAY 73-4506-d3) is a deuterium labeled Regorafenib. Regorafenib is a multi-targeted receptor tyrosine kinase inhibitor[1].

Product Specifications

CAS Number

1255386-16-3

Product Name Alternative

BAY 73-4506-d3

UNSPSC

12352005

Target

Autophagy; PDGFR; Raf; RET; VEGFR

Type

Isotope-Labeled Compounds

Related Pathways

Autophagy; MAPK/ERK Pathway; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Purity

98.0

Solubility

10 mM in DMSO|DMSO : 125mg/mL (ultrasonic)

Smiles

O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=C1)NC([2H])([2H])[2H]

Molecular Formula

C21H12D3ClF4N4O3

Molecular Weight

485.83

References & Citations

[1]Wilhelm SM, et al. Regorafenib (BAY 73-4506) : a new oral multikinase inhibitor of angiogenic, stromal and oncogenic receptor tyrosine kinases with potent preclinical antitumor activity. Int J Cancer, 2011, 129 (1), 245-255.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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