SP-471
SP-471 is a potent dengue virus (DENV) protease inhibitor with IC50 value of 18 μM. SP-471 inhibits both intermolecular and intramolecular protease processes of DENV[1].
Product Specifications
CAS Number
2768010-39-3
UNSPSC
12352005
Target
Dengue Virus; Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sp-471.html
Purity
99.79
Solubility
10 mM in DMSO
Smiles
N=C(C1=CC=CC(C2=CC=C3C(C4=C(N3CC5=CC=CC(Br)=C5)C=CC(C6=CC=CC(C(N)=N)=C6)=C4)=C2)=C1)N
Molecular Formula
C33H26BrN5
Molecular Weight
572.50
References & Citations
[1]Swarbrick C, Zogali V, Chan KWK, et al. Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease. Eur J Med Chem. 2021;224:113695.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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