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Antiproliferative agent-13

Antiproliferative agent-13 (compound 16c) shows an antiproliferative activity against human A375 cells with an IC50 value of 32.7 nM. Antiproliferative agent-13 can be used for the research of cancer[1].

Product Specifications

CAS Number

[663214-48-0]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antiproliferative-agent-13.html

Purity

99.09

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N#CC1=C(N)OC2=CC(OCO3)=C3C=C2C1C4=CC(OC)=C(OC)C(OC)=C4

Molecular Formula

C20H18N2O6

Molecular Weight

382.37

Precautions

H302, H315, H319

References & Citations

[1]Zhang H, et al. Design, synthesis and characterization of potent microtubule inhibitors with dual anti-proliferative and anti-angiogenic activities. Eur J Med Chem. 2018 Sep 5;157:380-396

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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