Adenosine-15N5

Adenosine-15N5 (Adenine riboside-15N5; D-Adenosine-15N5) is the 15N labled Adenosine (HY-B0228) . Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation[1][2].

Product Specifications

CAS Number

[168566-57-2]

Product Name Alternative

Adenine riboside-15N5; D-Adenosine-15N5

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/adenosine-15n5.html

Purity

99.90

Solubility

DMSO : 33.33 mg/mL (ultrasonic; warming)

Smiles

O[C@H]1[C@@H](O)[C@H]([15N]2C3=[15N]C=[15N]C([15NH2])=C3[15N]=C2)O[C@@H]1CO

Molecular Formula

C10H13 15N5O4

Molecular Weight

272.21

References & Citations

[1]Zhou XT, et al. Inhibition of autophagy enhances adenosine induced apoptosis in human hepatoblastoma HepG2 cells. Oncol Rep. 2019;41 (2) :829-838.|[2]Eltzschig HK. Adenosine: an old drug newly discovered. Anesthesiology. 2009;111 (4) :904-915.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.