9-PAHSA

9-PAHSA is an orally available anti-inflammatory lipid that lowers blood sugar and reduces inflammation. 9-PAHSA also improved carotid vascular calcification and attenuates cardiac hypertrophy and dysfunction in db/db mice. 9-PAHSA increases the viability of steatosis primary mouse hepatocytes (PMH) . 9-PAHSA can be used in research on diabetes, inflammation, and cardiovascular disease[1][2].

Product Specifications

CAS Number

[1481636-31-0]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H331, H336, H351, H361, H372, H412

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/9-pahsa.html

Purity

99.88

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 80°C)

Smiles

OC(CCCCCCCC(CCCCCCCCC)OC(CCCCCCCCCCCCCCC)=O)=O

Molecular Formula

C34H66O4

Molecular Weight

538.89

Precautions

H302, H315, H319, H331, H336, H351, H361, H372, H412

References & Citations

[1]Wang YM, et al. 9-PAHSA Improves Cardiovascular Complications by Promoting Autophagic Flux and Reducing Myocardial Hypertrophy in Db/Db Mice. Front Pharmacol. 2021 Nov 15;12:754387.|[2]Schultz Moreira AR, et al. 9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes. Int J Mol Sci. 2020 Nov 5;21 (21) :8279.