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TNIK-IN-2

TNIK-IN-2 is a Traf2- and Nck-interacting protein kinase (TNIK) inhibitor, with an IC50 of 1.3337 μM. TNIK-IN-2 can be used for the study of colorectal cancer (CRC) [1].

Product Specifications

CAS Number

2754265-76-2

UNSPSC

12352005

Target

Ser/Thr Protease

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tnik-in-2.html

Purity

99.68

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

COC1=CC(NC(C2=CC=C(C=C2OC)C3=CC4=C(NC=C4)N=C3)=O)=CC=C1

Molecular Formula

C22H19N3O3

Molecular Weight

373.40

References & Citations

[1]Li Y, et, al. Discovery of 3,4-Dihydrobenzo[ f][1,4]oxazepin-5 (2 H) -one Derivatives as a New Class of Selective TNIK Inhibitors and Evaluation of Their Anti-Colorectal Cancer Effects. J Med Chem. 2022 Jan 5.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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