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Thiorphan

Product Specifications

UNSPSC Description

Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[1].

Target Antigen

Neprilysin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/thiorphan.html

Purity

99.67

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

SCC(C(NCC(O)=O)=O)CC1=CC=CC=C1

Molecular Weight

253.323

References & Citations

[1]Whyteside AR, Turner AJ. Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences. FEBS Lett. 2008 Jul 9;582(16):2382-6.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W013375/Thiorphan-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W013375/Thiorphan-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

76721-89-6

Available Sizes

Curated Selection

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