Thiorphan
Product Specifications
UNSPSC Description
Thiorphan is a selective NEP (neprilysin) inhibitor with an IC50 of 6.9 nM[1].
Target Antigen
Neprilysin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thiorphan.html
Purity
99.67
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
SCC(C(NCC(O)=O)=O)CC1=CC=CC=C1
Molecular Weight
253.323
References & Citations
[1]Whyteside AR, Turner AJ. Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences. FEBS Lett. 2008 Jul 9;582(16):2382-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W013375/Thiorphan-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W013375/Thiorphan-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
76721-89-6
Available Sizes
Curated Selection
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