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4-Maleimidobutyric acid

Selected Variant

HY-W037355-01

Size: 5 g

4-Maleimidobutyric acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

57078-98-5

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-maleimidobutyric-acid.html

Purity

99.86

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(O)CCCN1C(C=CC1=O)=O

Molecular Formula

C8H9NO4

Molecular Weight

183.16

Precautions

H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Available Sizes

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