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MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan

MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan is a pharmaceutical composition containing antibody agent conjugate (ADC) . (extracted from patent WO2021190581 Example 1-8) [1].

Product Specifications

CAS Number

[2414254-41-2]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Topoisomerase

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mc-gly-gly-phe-gly-amide-cyclopropanol-amide-exatecan.html

Purity

99.16

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(C1(CC1)OCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95

Molecular Formula

C54H58FN9O13

Molecular Weight

1060.09

References & Citations

[1]Yue Zhanlong, et al. Pharmaceutical composition comprising antibody drug conjugate and use thereof. WO2021190581A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Camptothecins

Available Sizes

Curated Selection

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