MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan
MC-Gly-Gly-Phe-Gly-amide-cyclopropanol-amide-Exatecan is a pharmaceutical composition containing antibody agent conjugate (ADC) . (extracted from patent WO2021190581 Example 1-8) [1].
Product Specifications
CAS Number
2414254-41-2
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC; Topoisomerase
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mc-gly-gly-phe-gly-amide-cyclopropanol-amide-exatecan.html
Purity
99.16
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1(CC1)OCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN2C(C=CC2=O)=O)=O)=O)=O)CC3=CC=CC=C3)=O)=O)N[C@@H]4C5=C6C(C(N7C6)=CC([C@](O)(C(OC8)=O)CC)=C8C7=O)=NC9=CC(F)=C(C)C(CC4)=C95
Molecular Formula
C54H58FN9O13
Molecular Weight
1060.09
References & Citations
[1]Yue Zhanlong, et al. Pharmaceutical composition comprising antibody drug conjugate and use thereof. WO2021190581A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
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