Bax inhibitor peptide V5
Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
Product Specifications
CAS Number
579492-81-2
Product Name Alternative
BIP-V5; BAX Inhibiting Peptide V5
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Bax-inhibitor-peptide-V5.html
Purity
99.90
Solubility
DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H](CCC1)N1C([C@@H](N)C(C)C)=O)N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCCN)=O)=O
Molecular Formula
C27H50N6O6S
Molecular Weight
586.79
Precautions
H302, H315, H319, H335
References & Citations
[1]Jo MJ, et al. Regulation of cancer cell death by a novel compound, C604, in a c-Myc-overexpressing cellular environment. Eur J Pharmacol. 2015 Dec 15;769:257-65.|[2]Rivas-Carrillo JD, et al. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007 May;56 (5) :1259-67. Epub 2007 Feb 7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Bax
Available Sizes
Frequently Asked Questions
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