Bax inhibitor peptide V5

Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.

Product Specifications

CAS Number

[579492-81-2]

Product Name Alternative

BIP-V5; BAX Inhibiting Peptide V5

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Bcl-2 Family

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Bax-inhibitor-peptide-V5.html

Purity

99.90

Solubility

DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H](CCC1)N1C([C@@H](N)C(C)C)=O)N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCCCN)=O)=O

Molecular Formula

C27H50N6O6S

Molecular Weight

586.79

Precautions

H302, H315, H319, H335

References & Citations

[1]Jo MJ, et al. Regulation of cancer cell death by a novel compound, C604, in a c-Myc-overexpressing cellular environment. Eur J Pharmacol. 2015 Dec 15;769:257-65.|[2]Rivas-Carrillo JD, et al. Cell-permeable pentapeptide V5 inhibits apoptosis and enhances insulin secretion, allowing experimental single-donor islet transplantation in mice. Diabetes. 2007 May;56 (5) :1259-67. Epub 2007 Feb 7.