Selgantolimod
Selgantolimod (GS-9688) is an orally active, potent and selective toll-like receptor 8 (TLR8) agonist for the treatment of hepatitis B virus (HBV) and human immunodeficiency virus (HIV) infection[1][2][3].
Product Specifications
CAS Number
2004677-13-6
Product Name Alternative
GS-9688
UNSPSC
12352005
Target
HBV; Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Anti-infection; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/selgantolimod.html
Purity
98.18
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
C[C@@](CCCC)(CO)NC1=NC(N)=NC2=C1N=CC(F)=C2
Molecular Formula
C14H20FN5O
Molecular Weight
293.34
References & Citations
[1]Jules Levin. Efficacy and Safety of Oral TLR8 Agonist Selgantolimod in Virally Suppressed Adult Patients With Chronic Hepatitis B: a Phase 2, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study. 2019 Nov 8-12.|[2]Benjamin Ryan. Selgantolimod Shows Promise as Treatment for Hepatitis B. November 18, 2019.|[3]Romas Geleziunas, et al. Modulators of toll-like receptors for the treatment of hiv. US20170071944A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
TLR8
Available Sizes
Frequently Asked Questions
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