D-Lin-MC3-DMA
D-Lin-MC3-DMA, an ionizable cationic lipid, is a potent siRNA delivery vehicle.
Product Specifications
CAS Number
1224606-06-7
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/D-Lin-MC3-DMA.html
Purity
99.9100
Solubility
DMSO : 200 mg/mL (ultrasonic) |Ethanol : 125 mg/mL (ultrasonic)
Smiles
O=C(OC(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC)CCCN(C)C
Molecular Formula
C43H79NO2
Molecular Weight
642.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Kulkarni JA, et al. Design of lipid nanoparticles for in vitro and in vivo delivery of plasmid DNA. Nanomedicine. 2017 May;13 (4) :1377-1387.|[2]Ferraresso F, Strilchuk AW, Juang LJ, Poole LG, Luyendyk JP, Kastrup CJ. Comparison of DLin-MC3-DMA and ALC-0315 for siRNA Delivery to Hepatocytes and Hepatic Stellate Cells. Mol Pharm. 2022;19 (7) :2175-2182.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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