What is the catalog number for Valspodar?

The catalog number for Valspodar is HY-17384.

What sizes are available for Valspodar?

Valspodar is available in the following size(s): 1 mg, 5 mg, 10 mg, 25 mg, 50 mg.

How many pack sizes does Valspodar come in?

Valspodar is available in 5 different pack sizes.

Is Valspodar in stock?

Valspodar is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Valspodar?

Valspodar is manufactured by QuantiMol.

What is the estimated delivery time for Valspodar?

Estimated delivery time for Valspodar is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Valspodar?

The safety data sheet for Valspodar is available here: http://file.medchemexpress.com/batch_PDF/HY-17384/Valspodar-SDS-MedChemExpress.pdf.

Valspodar

Valspodar (PSC 833) is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer.

Product Specifications

CAS Number

121584-18-7

Product Name Alternative

PSC 833

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Valspodar.html

Concentration

10mM

Purity

99.27

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H](C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N(C)C([C@H](C(C)C)NC([C@H](CC(C)C)N(C)C(CN(C)C([C@H](C(C)C)N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)N(C)[C@@H](C([C@H](C)C/C=C/C)=O)C1=O

Molecular Formula

C63H111N11O12

Molecular Weight

1214.62

Precautions

H302, H315, H319, H335

References & Citations

[1]Bajelan E, et al. Co-delivery of NSC 123127 and PSC 833 (Valspodar) by stealth nanoliposomes for efficient overcoming of multidrug resistance. J Pharm Pharm Sci. 2012 Sep;15 (4) :568-82.|[2]PermissionsZ., et al. Pharmacokinetics of PSC 833 (valspodar) in its Cremophor EL formulation in rat.2010,40 (1) :55-61.|[3]Fei Shen, et al. Dynamic Assessment of NSC 279836 Resistance and Modulation of Multidrug Resistance by Valspodar (PSC833) in Multidrug Resistance Human Cancer Cells. JPET August 2009,330 (2) : 423-429