TLR7/8-IN-1
TLR7/8-IN-1 is a crystalline from of a TLR7/TLR8 inhibitor extracted from patent WO2019220390, compound 2b. TLR7/8-IN-1 can be used for the research of autoimmune disease[1].
Product Specifications
CAS Number
[2205095-75-4]
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/tlr7-8-in-1.html
Purity
99.92
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=C([C@@H]1COCCN1)NC(CC2)(CC3)CCC23CN4C5=C(CN(C6=C7C(N(N=C7)C)=NC(C)=C6)CC5)C(C)=N4
Molecular Formula
C29H40N8O2
Molecular Weight
532.68
References & Citations
[1]WO2019220390
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7; TLR8
Available Sizes
Curated Selection
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