PF-04885614
PF-04885614 is a potent NaV1.8 inhibitor, extracted from patent US2018328915. PF-04885614 has potential for neurological and neurodevelopmental diseases treatment[1].
Product Specifications
CAS Number
[1480833-70-2]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pf-04885614.html
Purity
97.00
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
NC(C)(C)C1=NC=C(C2=CC=C(OC(F)(F)F)C=C2)N1
Molecular Formula
C13H14F3N3O
Molecular Weight
285.26
Precautions
H315, H319
References & Citations
[1]Brady MAHER, et al. Treatment of Neurological and Neurodevelopmental Diseases and Disorders Associated with Aberrant Ion Channel Expression and Activity. US20180328915A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.8
Available Sizes
Curated Selection
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