Alendronic acid
Product Specifications
UNSPSC Description
Alendronic acid, a bisphosphonate, is a farnesyl diphosphate synthase (FDPS) inhibitor. Alendronic acid inhibits osteoclast-mediated bone resorption. Alendronic acid shows efficacy in postmenopausal osteoporosis, malignant hypercalcemia and Paget’s disease[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alendronic-acid.html
Purity
98.0
Solubility
H2O : 3.7 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
OC(P(O)(O)=O)(CCCN)P(O)(O)=O
Molecular Weight
249.10
References & Citations
[1]Teixeira S, et al. Alendronic Acid as Ionic Liquid: New Perspective on Osteosarcoma. Pharmaceutics. 2020 Mar 24;12(3). pii: E293.|[2]Duckworth AD, et al. Effect of Alendronic Acid on Fracture Healing: A Multicenter Randomized Placebo-Controlled Trial. J Bone Miner Res. 2019 Jun;34(6):1025-1032.Cell Rep. 2022 Oct 25;41(4):111508.|Am J Physiol Endocrinol Metab. 2024 May 8.|Int J Mol Sci. 2024 Jul 16;25(14):7798.|J Biol Chem. 2019 Jul 19;294(29):11240-11247.|J Med Chem. 2024 Aug 26.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-B0631/Alendronic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-B0631/Alendronic-acid-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
66376-36-1
Available Sizes
Curated Selection
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