CYM50179

CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].

Product Specifications

CAS Number

[1355026-47-9]

UNSPSC

12352005

Hazard Statement

H301, H318, H413

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cym50179.html

Concentration

10mM

Purity

96.06

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

ClC1=CC(Cl)=C(C=C1)OCCOC2=C(N=C(C=C2)Br)Br

Molecular Formula

C13H9Br2Cl2NO2

Molecular Weight

441.93

Precautions

H301, H318, H413

References & Citations

[1]Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :537-42.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

S1PR4

Available Sizes

Curated Selection

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