CYM50179
CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].
Product Specifications
CAS Number
1355026-47-9
UNSPSC
12352005
Hazard Statement
H301, H318, H413
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cym50179.html
Concentration
10mM
Purity
96.06
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
ClC1=CC(Cl)=C(C=C1)OCCOC2=C(N=C(C=C2)Br)Br
Molecular Formula
C13H9Br2Cl2NO2
Molecular Weight
441.93
Precautions
H301, H318, H413
References & Citations
[1]Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22 (1) :537-42.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
S1PR4
Available Sizes
Frequently Asked Questions
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