O-Nornuciferine

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].

Product Specifications

CAS Number

[3153-55-7]

UNSPSC

12352005

Target

Endogenous Metabolite; Potassium Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/o-nornuciferine.html

Purity

99.85

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

OC1=C(OC)C2=C3C(CCN(C)[C@]3([H])CC4=CC=CC=C24)=C1

Molecular Formula

C18H19NO2

Molecular Weight

281.35

References & Citations

[1]Ulrike Grienke, et al. Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63 (23) :5634-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

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