O-Nornuciferine
O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].
Product Specifications
CAS Number
[3153-55-7]
UNSPSC
12352005
Target
Endogenous Metabolite; Potassium Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/o-nornuciferine.html
Purity
99.85
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=C(OC)C2=C3C(CCN(C)[C@]3([H])CC4=CC=CC=C24)=C1
Molecular Formula
C18H19NO2
Molecular Weight
281.35
References & Citations
[1]Ulrike Grienke, et al. Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63 (23) :5634-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Curated Selection
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