Diadenosine pentaphosphate (pentasodium)

Diadenosine pentaphosphate pentasodium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2–7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes[1][2].

Product Specifications

CAS Number

[4097-04-5]

Product Name Alternative

TAK-013

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/diadenosine-pentaphosphate-pentasodium.html

Purity

97.0

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1COP(OP(OP(OP(OP(OC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C6=NC=NC(N)=C6N=C5)O4)(O[Na])=O)(O[Na])=O)(O[Na])=O)(O[Na])=O)(O[Na])=O

Molecular Formula

C20H24N10Na5O22P5

Molecular Weight

1026.28

References & Citations

[1]L Giraldez, et al. Adenosine triphosphate and diadenosine pentaphosphate induce [Ca (2+) ] (i) increase in rat basal ganglia aminergic terminals. J Neurosci Res. 2001 Apr 15;64 (2) :174-82.|[2]Jesús Pintor, et al. Presence of diadenosine polyphosphates in human tears. Pflugers Arch. 2002 Jan;443 (3) :432-6.