Anti-FBG2 Antibody

Rabbit Polyclonal Antibody specific to FBG2 (F Box 2)

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

F-box protein that recognizes sugar chains 2, F-box/G-domain protein 2

Gene Name

FBXO6

NCBI Gene ID

UniProt

Q9NRD1

Cellular Locus

Cytoplasm

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to amino acids 268-284 of human FBG2.

Target Antigen

F-box only protein 6

Target

FBG2

Clonality

Polyclonal

Type

Antibody

Applications

Field of Research

Neuroscience

Purification Method

Purified by Protein G affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Function

Substrate-rPubMed:18203720, PubMed:19716789}.

Additionnal Information

Immunoblotting : use at 1-5ug/ml dilution. A band of approximately 34 kDa is detected. <br><br>These are recommended concentrations. User should determine optimal concentration for their applications.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze- thaw cycles.

Specificity

This antibody recognizes human, mouse, and rat FBG2.

Formulation

PBS, pH 7.4.

Buffer pH

pH 7.4

Target Background

F-box proteins, critical components of the conserved ubiquitin-protein ligase complex SCF (Skp1/Cdc53-Cullin1/F- box), recruit substrates for ubiquitination and consequent degradation through their specific protein-protein interaction domains. Novel human F-box proteins named FBG1, FBG2, FBG3, FBG4 and FBG5 constitute a subfamily of mammalian F-box proteins. FBG genes are expressed in a limited number of human tissues including kidney, liver, brain and muscle tissues.