DBCO- (PEG) 3-VC-PAB-MMAE
DBCO- (PEG) 3-VC-PAB-MMAE is a agent-linker conjugate for ADC. DBCO- (PEG) 3-VC-PAB-MMAE is made by Monomethyl auristatin E conjugats to DBCO- (PEG) 3-vc-PAB linker. DBCO- (PEG) 3-VC-PAB-MMAE can be used for the research of cancer[1]. DBCO- (PEG) 3-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Product Specifications
CAS Number
2754384-60-4
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/DBCO-_PEG_3-VC-PAB-MMAE.html
Purity
99.60
Solubility
DMSO : 60 mg/mL (ultrasonic)
Smiles
Molecular Formula
C86H124N12O18
Molecular Weight
1613.97
References & Citations
[1]Karsten L, et al. Bivalent EGFR-Targeting DARPin-MMAE Conjugates. Int J Mol Sci. 2022 Feb 23;23 (5) :2468.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Auristatin
Available Sizes
Frequently Asked Questions
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