DBCO- (PEG) 3-VC-PAB-MMAE

DBCO- (PEG) 3-VC-PAB-MMAE is a agent-linker conjugate for ADC. DBCO- (PEG) 3-VC-PAB-MMAE is made by Monomethyl auristatin E (HY-15162) conjugats to DBCO- (PEG) 3-vc-PAB linker. DBCO- (PEG) 3-VC-PAB-MMAE can be used for the research of cancer[1]. DBCO- (PEG) 3-VC-PAB-MMAE is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Product Specifications

CAS Number

[2754384-60-4]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/DBCO-_PEG_3-VC-PAB-MMAE.html

Purity

99.60

Solubility

DMSO : 60 mg/mL (ultrasonic)

Smiles

CC[C@H](C)[C@@H]([C@@H](CC(N1[C@@H](CCC1)[C@@H]([C@@H](C)C(N[C@H](C)[C@@H](O)C2=CC=CC=C2)=O)OC)=O)OC)N(C([C@H](C(C)C)NC([C@H](C(C)C)N(C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCNC(CCC(N(C4)C5=C(C=CC=C5)C#CC6=C4C=CC=C6)=O)=O)=O)=O)=O)C=C3)=O)C)=O)=O)C