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DNA Gyrase-IN-13

DNA Gyrase-IN-13 (compound 1b) is a DNA Gyrase inhibitor. DNA Gyrase-IN-13 has antibacterial activity. DNA Gyrase-IN-13 has an IC50 value of 1.81 μM for Staphylococcus aureus DNA gyrase[1].

Product Specifications

CAS Number

2247443-72-5

UNSPSC

12352211

Target

Bacterial; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Anti-infection; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dna-gyrase-in-13.html

Smiles

CCCCCOC1=CC=C(C=C1)C(NNC(NC(C)=O)=S)=O

Molecular Formula

C15H21N3O3S

Molecular Weight

323.41

References & Citations

[1]Zhang G, et al. Discovery of novel 1,4-dicarbonylthiosemicarbazides as DNA gyrase inhibitors for the treatment of MRSA infection. Eur J Med Chem. 2024 Sep 28;280:116905.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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