Biotinylated Human ANGPTL7 / CDT6 Protein, Mouse IgG2a Fc, Avitag™

Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

Product Specifications

Background

Specifications

This protein carries a mouse IgG2a Fc tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 65.8 kDa. The protein migrates as 60 kDa and 70 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

O43827-1

Expression Region

Gln 27 - Pro 346

Host

HEK293

Target

ANGPTL7

Conjugation

Biotin-labeled

Tag

C-mFc (mIgG2a) & C-Avi

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized Human LILRB2, Fc Tag at 5 μg/mL (100 μL/well) can bind Biotinylated Human ANGPTL7, Mouse IgG2a Fc,Avitag (Cat. No. AN7-H82F3) with a linear range of 0.156-2.5 μg/mL (QC tested).