L-Cysteine

L-Cysteine (Cysteine) is an orally active conditionally essential amino acid with hypoglycemic effects, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H2S pathway. L-Cysteine suppresses ghrelin and reduces appetite in rodents and humans. L-Cysteine can be used as an anorectic agent[1][2][3][4].

Product Specifications

CAS Number

[52-90-4]

Product Name Alternative

Cysteine

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; ERK

Type

Natural Products

Related Pathways

MAPK/ERK Pathway; Metabolic Enzyme/Protease; Stem Cell/Wnt

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/L-Cysteine.html

Purity

99.3

Solubility

H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N[C@@H](CS)C(O)=O

Molecular Formula

C3H7NO2S

Molecular Weight

121.16

Precautions

H302, H315, H319, H335

References & Citations

[1]McGavigan AK, et al. L-cysteine suppresses ghrelin and reduces appetite in rodents and humans. Int J Obes (Lond) . 2015 Mar;39 (3) :447-55.|[2]Wang Z, et al. L-Cysteine promotes the proliferation and differentiation of neural stem cells via the CBS/H₂S pathway. Neuroscience. 2013 May 1;237:106-17.|[3]Gazit V, et al. L-cysteine increases glucose uptake in mouse soleus muscle and SH-SY5Y cells. Metab Brain Dis. 2003 Sep;18 (3) :221-31.|[4]Takemoto Y. The central effect of L-cysteine on cardiovascular system of the conscious rat. Jpn J Physiol. 1995;45 (5) :771-83.