Anthraquinone

Anthraquinone is used as a precursor for dye formation and agrochemicals, existing in different organisms, such as bacteria, fungi, plants, and some animals. Anthraquinone has biological activities: anticancer, antiinflammatory, diuretic, antiarthritic, antifungal, antibacterial, antimalarial and antioxidant. Anthraquinone also plays an important role in the primary metabolism of plants by acting on the electron transport chain through the inhibition of energy transfer in the photosynthetic process. Anthraquinone can intercalates into DNA and inhibits the topoisomerase II (topo II) enzyme, resulting in cell death via Apoptosis[1][2][3][4].

Product Specifications

CAS Number

[84-65-1]

UNSPSC

12352005

Hazard Statement

H317, H350

Target

Apoptosis; Topoisomerase; Virus Protease

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis; Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anthraquinone.html

Purity

99.97

Solubility

DMSO : 2 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=C(C=CC=C2)C(C3=CC=CC=C13)=O

Molecular Formula

C14H8O2

Molecular Weight

208.22

Precautions

H317, H350

References & Citations

[1]Diaz-Munoz G, et al. Anthraquinones: an overview[J]. Studies in natural products chemistry, 2018, 58: 313-338.|[2]Yen G C, Duh P D, Chuang D Y. Antioxidant activity of anthraquinones and anthrone[J]. Food chemistry, 2000, 70 (4) : 437-441.|[3]Andersen DO, et al. In vitro virucidal activity of selected anthraquinones and anthraquinone derivatives. Antiviral Res. 1991 Sep;16 (2) :185-96. |[4]Barnard D L, et al. Evaluation of the antiviral activity of anthraquinones, anthrones and anthraquinone derivatives against human cytomegalovirus[J]. Antiviral research, 1992, 17 (1) : 63-77.