Hsa62
Hsa62 is a dual inhibitor for SIRT1 and SIRT2, with IC50 of 1.3 and 5.5 μM, respectively[1].
Product Specifications
CAS Number
[780822-35-7]
UNSPSC
12352005
Target
Sirtuin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsa62.html
Smiles
O=C1NC2=CC=C(S(=O)(NC3=CC(SC4=NN=CN4)=C(C5=C3C=CC=C5)O)=O)C=C2N1
Molecular Formula
C19H14N6O4S2
Molecular Weight
454.48
References & Citations
[1]Cai H, et al., Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells. J Chem Inf Model. 2023 Aug 14;63 (15) :4780-4790.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
SIRT1; SIRT2; SIRT3
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