Hsa62

Hsa62 is a dual inhibitor for SIRT1 and SIRT2, with IC50 of 1.3 and 5.5 μM, respectively[1].

Product Specifications

CAS Number

780822-35-7

UNSPSC

12352005

Target

Sirtuin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hsa62.html

Smiles

O=C1NC2=CC=C(S(=O)(NC3=CC(SC4=NN=CN4)=C(C5=C3C=CC=C5)O)=O)C=C2N1

Molecular Formula

C19H14N6O4S2

Molecular Weight

454.48

References & Citations

[1]Cai H, et al., Discovery of Novel SIRT1/2 Inhibitors with Effective Cytotoxicity against Human Leukemia Cells. J Chem Inf Model. 2023 Aug 14;63 (15) :4780-4790.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SIRT1; SIRT2; SIRT3

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