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GCN2-IN-1

GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of IC50 of 0.3-3 μM in the cell assay[1].

Product Specifications

CAS Number

1448693-69-3

Product Name Alternative

A-92

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Eukaryotic Initiation Factor (eIF)

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/GCN2-IN-1.html

Purity

99.46

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C1(NC2=CN(C3CCOCC3)N=C2)=NC=C(N=NN4C5=CC6=C(C=C5)C=NN6)C4=N1

Molecular Formula

C19H18N10O

Molecular Weight

402.41

Precautions

H315, H319, H320

References & Citations

[1]Dieter Dorsch, et al. Triazolo[4,5-d]pyrimidine derivatives. WO2013110309A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

EIF2

Available Sizes

Frequently Asked Questions

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