GCN2-IN-1
GCN2-IN-1 (A-92) is a potent general control nonderepressible 2 kinase (GCN2) inhibitor with an IC50 of IC50 of 0.3-3 μM in the cell assay[1].
Product Specifications
CAS Number
[1448693-69-3]
Product Name Alternative
A-92
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Eukaryotic Initiation Factor (eIF)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/GCN2-IN-1.html
Purity
99.46
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C1(NC2=CN(C3CCOCC3)N=C2)=NC=C(N=NN4C5=CC6=C(C=C5)C=NN6)C4=N1
Molecular Formula
C19H18N10O
Molecular Weight
402.41
Precautions
H315, H319, H320
References & Citations
[1]Dieter Dorsch, et al. Triazolo[4,5-d]pyrimidine derivatives. WO2013110309A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EIF2
Available Sizes
Curated Selection
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