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IONIS PTP1BRx (sodium)

IONIS PTP1BRx (ISIS 404173) sodium is an antisense inhibitor of protein tyrosine phosphatase 1B (PTP-1B) . IONIS PTP1BRx sodium shows antidiabetic activity, and can be used for the study of insulin resistance and type 2 diabetes mellitus associated with obesity[1].

Product Specifications

Product Name Alternative

ISIS 404173 (sodium)

UNSPSC

12352208

Target

Phosphatase

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ionis-ptp1brx-sodium.html

Smiles

[IONISPTP1BRx(sodium)]

References & Citations

[1]Stanley T Crooke, et al. The Effects of 2'-O-Methoxyethyl Oligonucleotides on Renal Function in Humans. Nucleic Acid Ther. 2018 Feb;28 (1) :10-22.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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