Icapamespib
Product Specifications
UNSPSC Description
Icapamespib (PU-HZ151) is a potent HSP90 inhibitor with an EC50 of 5 nM. Icapamespib is able to cross blood-brain barrier[1].
Target Antigen
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/icapamespib.html
Smiles
IC1=C(SC2=NC3=C(N)N=CN=C3N2CCNCC(C)(C)C)C=C4OCOC4=C1
Molecular Weight
526.39
References & Citations
[1]Bolaender A, et al. Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system. Nat Commun. 2021;12(1):4669. Published 2021 Aug 3.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137441/Icapamespib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137441/Icapamespib-SDS-MedChemExpress.pdf
CAS Number
1000999-96-1
Available Sizes
Curated Selection
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