EWP 815
EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins (1,4) P2 phosphatase and Ins (1,4,5) P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity[1][2].
Product Specifications
CAS Number
20231-01-0
UNSPSC
12352005
Target
Dopamine β-hydroxylase; Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ewp-815.html
Purity
98.25
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
S=C(N1CCN(C)CC1)SSC(N2CCN(C)CC2)=S
Molecular Formula
C12H22N4S4
Molecular Weight
350.59
References & Citations
[1]Fowler CJ, et al. Inhibition of inositol 1,4,5-trisphosphate 5-phosphatase by micromolar concentrations of disulfiram and its analogues. Biochem J. 1993 Feb 1;289 (Pt 3) (Pt 3) :853-9. |[2]Carlsson A, et al. On the beta-hydroxylation of (+-) -alpha-methyldopamine in vivo. Eur J Pharmacol. 1968 Dec;5 (1) :85-92.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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