ZINC49534341

ZINC49534341 is a MRGPRX2 antagonist, with a Ki of 32 nM[1].

Product Specifications

CAS Number

[1274013-03-4]

UNSPSC

12352005

Hazard Statement

H302, H312, H315, H319, H332, H335

Target

Mas-related G-protein-coupled Receptor (MRGPR)

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/zinc49534341.html

Purity

99.13

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N(CC2=NC=CS2)C(NC3=C1C=CC=C3)=S

Molecular Formula

C12H9N3OS2

Molecular Weight

275.35

Precautions

H302, H312, H315, H319, H332, H335

References & Citations

[1]Brian K. Shoichet, et al. Mrgprx2 antagonists and uses thereof. Patent, WO2023039448A1.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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