What is the catalog number for Anandamide-d8?

The catalog number for Anandamide-d8 is HY-10863S.

What sizes are available for Anandamide-d8?

Anandamide-d8 is available in the following size(s): 500 μg (2.81 mM x 500 μL in Methyl Acetate).

Is Anandamide-d8 in stock?

Anandamide-d8 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anandamide-d8?

Anandamide-d8 is manufactured by QuantiMol.

What is the estimated delivery time for Anandamide-d8?

Estimated delivery time for Anandamide-d8 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Anandamide-d8?

The safety data sheet for Anandamide-d8 is available here: http://file.medchemexpress.com/batch_PDF/HY-10863S/Anandamide-d8-SDS-MedChemExpress.pdf.

Anandamide-d8

Anandamide-d8 is a deuterated labeled Anandamide[1]. Anandamide is an endocannabinoid. Anandamide modulates both neuronal and immune functions through two protein-coupled cannabinoid receptors (CB1 and CB2) . Anandamide can activate numerous other receptors like PPARS, TRPV1, and GPR18/GPR55. Anandamide also has potential anti-fungal and anti-inflammatory activities. Anandamide can be used for the research of Alzheimer’s disease (AD) and ulcerative colitis[2][3][4][5][6].

Product Specifications

CAS Number

924894-98-4

Product Name Alternative

AEA-d8

UNSPSC

12352211

Hazard Statement

H225, H319, H336

Target

Cannabinoid Receptor; Endogenous Metabolite; Fungal; GPR55; Isotope-Labeled Compounds; PPAR; Tau Protein; TRP Channel

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Infection

Concentration

2.81 mM * 500 μL in Methyl acetate

Purity

99.90

Smiles

CCCCC/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\C/C([2H])=C([2H])\CCCC(NCCO)=O

Molecular Formula

C22H29D8NO2

Molecular Weight

355.58

Precautions

H225, H319, H336

References & Citations

[1]Malek N, et al. Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures. Neural Plast. 2015;2015:130639.|[2]Moreira-Silva D, et al. Anandamide Effects in a Streptozotocin-Induced Alzheimer's Disease-Like Sporadic Dementia in Rats. Front Neurosci. 2018 Sep 21;12:653.|[3]Troy-Fioramonti S, et al. Acute activation of cannabinoid receptors by Anandamide reduces gastrointestinal motility and improves postprandial glycemia in mice. Diabetes. 2015 Mar;64 (3) :808-18.|[4]Sionov RV, et al. Anandamide prevents the adhesion of filamentous Candida albicans to cervical epithelial cells. Sci Rep. 2020 Aug 13;10 (1) :13728.|[5]Pflüger-Müller B, et al. The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells. Basic Res Cardiol. 2020 Apr 22;115 (3) :34.|[6]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.