SCR-7952

SCR-7952 is a MAT2A inhibitor, with IC50 of 18.7 nM. SCR-7952 can be used in anti-cancer research[1].

Product Specifications

CAS Number

[2798856-04-7]

UNSPSC

12352005

Target

Methionine Adenosyltransferase (MAT)

Type

Reference compound

Related Pathways

Epigenetics; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/scr-7952.html

Purity

99.77

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1N(C2=CC=CN=C2C3CC3)C4=C(C=CC(Cl)=C4)C5=C1N=CN5C

Molecular Formula

C19H15ClN4O

Molecular Weight

350.80

References & Citations

[1]Yu Z, et al. SCR-7952, a highly selective MAT2A inhibitor, demonstrates synergistic antitumor activities in combination with the S-adenosylmethionine-competitive or the methylthioadenosine-cooperative protein arginine methyltransferase 5 inhibitors in methylthioadenosine phosphorylase-deleted tumors. MedComm (2020) . 2024 Sep 20;5 (10) :e705.