(Rac) -BL-918
(Rac) -BL-918 is the racemate of BL-918. BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1), inducing cytoprotective autophagy for Parkinson’s disease treatment[1].
Product Specifications
CAS Number
2435589-07-2
UNSPSC
12352005
Target
Autophagy; ULK
Type
Reference compound
Related Pathways
Autophagy
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-bl-918.html
Purity
98.88
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(NC1=CC=C(F)C=C1F)C(NC(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=S)C3=CC=CC=C3
Molecular Formula
C23H15F8N3OS
Molecular Weight
533.44
References & Citations
[1]Ouyang L, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment. J Med Chem. 2018 Apr 12;61 (7) :2776-2792.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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