(Rac) -BL-918
(Rac) -BL-918 is the racemate of BL-918. BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1), inducing cytoprotective autophagy for Parkinson’s disease treatment[1].
Product Specifications
CAS Number
2435589-07-2
UNSPSC
12352005
Target
Autophagy; ULK
Type
Reference compound
Related Pathways
Autophagy
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rac-bl-918.html
Purity
98.88
Solubility
DMSO : ≥ 125 mg/mL
Smiles
O=C(NC1=CC=C(F)C=C1F)C(NC(NC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)=S)C3=CC=CC=C3
Molecular Formula
C23H15F8N3OS
Molecular Weight
533.44
References & Citations
[1]Ouyang L, et al. Small-Molecule Activator of UNC-51-Like Kinase 1 (ULK1) That Induces Cytoprotective Autophagy for Parkinson's Disease Treatment. J Med Chem. 2018 Apr 12;61 (7) :2776-2792.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSM040493 50 µg
Recombinant Mouse Cathepsin S/CTSS Protein (His Tag)
Sign In for Pricing
View Details 
HA750197 100 µL
Histone H3 (mono methyl R2) Recombinant Rabbit monoclonal Antibody
Sign In for Pricing
View Details